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Now in its third edition, this classic reference is the one-stop-shop for information on the foundations of medicinal chemistry for pharmaceutical researchers who are involved in drug development & discovery but do not have a background in medicinal chemistry. Wermuth aids pharmaceutical researchers and chemists in making faster more accurate identifications of the active substances that could potentially treat the disorder they are researching. New chapters on Drug Absorption & Transport, give pharmaceutical scientists the information on how potential drugs can move through the drug discovery/ development phases more quickly. This third edition still stands as the only source for practical aspects of medicinal chemistry by focusing on the daily problems met by the medicinal chemist in drug discovery.