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Retaining his excellent, proven approach, world-famous chemist and passionate teacher K.C. Nicolaou and his student Jason S. Chen compile here the important strategies and tools employed to construct complex molecules. Through 42 syntheses of 25 challenging natural products they explain the key steps of the synthetic pathway, highlighting the major developments for easier understanding, and contrasting these to other synthetic methods. Similar to its predecessors and completing a trilogy, this textbooks analyzes the syntheses in a didactic manner, with several chapters including mini-reviews of key methodologies, and an emphasis on the history, mechanism, scope, and generality of the reactions. In contrast to the first two volumes, this new one features full-color frontispieces.
A wonderful tool for learning and teaching, and a must-have for all current and future organic, medicinal and biological chemists.
From reviews of "Classics in Total Synthesis", Volumes I and II:
"...a volume, (...) which any chemist with an interest in synthetic organic chemistry will wish to acquire."
JACS
"...this superb book (...) will be an essential purchase for many organic chemists."
Nature
"... Classics II is undoubtedly an excellent bargain that is highly recommended to everybody interested in advanced organic chemistry..."
Angewandte Chemie